• Vervain: When ingested, vervain causes a vampire to become severely weak and feverish. Also, If a vampire's skin is exposed to vervain, it can result in burning them.

• Device: Invented by Jonathan Gilbert (Enchanted by Emily Bennett), the Device was a weapon designed to emit a high-frequency noise that could only be heard by vampires and werewolves.

• Decapitation: Removing the head of a vampire will result in its instant death.

• Magic: Witches are able to give supernatural aneurysms that cause the blood vessels of vampires to explode.

• Heart Extraction: If a vampire's heart is taken out, it will cause instant death.

• Fire or Sunlight: Fire burns normal vampires to death. Sunlight also burns normal vampires, and if they are exposed for too long will cause them to burst into flames and die.

• Wood: If a vampire is wounded by wood it will cause the vampire to become severely weak and if a vampire takes a wooden stake through its heart it will result in death.

• Uninvited Invitation: Vampires cannot enter a house without being invited in. If they are in the house without being invited in they will become disoriented.

• Werewolf Bite: The bite of a werewolf is extremely lethal to normal vampires.